The postdoctoral fellow will work on HIV 1 env vaccine development and modulation of B cell affinity maturation.He or she will explore humoral and cell mediated autoimmune responses induced by vaccination and underlying mechanisms of breaking immune tolerance. Mouse model immunization studies, immune sera analyses, FACS for immune cells analyses, B cell repertoire analysi

Technical proficiency, scientific creativity, collaboration with others and independent thought. Design, conduct, and troubleshoot hypothesis testing experiments. Design, conduct, and validate high throughput, hypothesis generating screens. Mentoring of research technicians and undergraduate students. Maintain detailed and understandable lab notebooks and records. Interpr

The ideal candidate will additionally possess excellent experimental planning and execution skills, good communications skills, an open and creative mind, and a desire to collaborate with others. The candidate will lead independent research projects, report progress and track deliverables, work to develop innovative approaches to advance the field of tumor immunology and

The Fischer Lab at Dana Farber Cancer Institute is a Structural and Chemical Biology lab that combines molecular biology, computational biology, structural biology and chemistry with various 'Omics' techniques such as proteomics to study the pathways and protein complexes involved in the regulation of protein abundance via the ubiquitin proteasome system that are often as

N/A Qualifications PhD degree in chemical biology or a related discipline Strong background in synthetic organic chemistry, to enable delivery of chemical probes Familiarity with chemical biology techniques used to assess interactions between proteins and small molecules. Experience in biochemical/biophysical assay development Experience in chemoproteomics is desirable Ex

Design and implement studies to evaluate determinants of pancreatic cancer risk and outcomes. Collaborate with other laboratory members with expertise in epidemiology, biostatistics, pathology, molecular biology, and functional genomics. Conduct analyses using statistical software, such as SAS, R, and others. Participate in group meetings and work collaboratively on large

Performing cell and molecular biology research including but not limited to 2D and 3D cell culture, genetic manipulation through shRNA/CRISPR, protein/RNA/DNA analyses including Western blotting, RNA seq, IP MS, and ChIP seq. Lentiviral transduction techniques for ORF overexpression experiments or RNAi and CRISPR Cas9 knockdown/knockout experiments. Performing a variety o

The position will involve the study of myeloid neoplasms and will lead to significant experience in a wide range of techniques, including cell culture, genome engineering, protein biochemistry, flow cytometry, genetic screening, RNAseq, proteomics, and human tissue biomarker analysis. Developing independence will be fostered and opportunities for inter laboratory, multidi

Conduct standardized biological, microbiological or biochemical tests and laboratory analyses, including the collection of information and samples from organic substances, such as blood, drugs, and animals. Isolate, identify and prepare specimens for examination. Analyze experimental data and interpret results to write reports and summaries of findings, including grant pr

None PATIENT CONTACT Provides direct care to patients SPECIAL WORKING CONDITIONS Works in an inpatient setting with possible exposure to infectious diseases through airborne transmission or contact with blood or body fluids. External and internal applicants, as well as position incumbents who become disabled as defined under the Americans With Disabilities Act, must be ab

In collaboration with a physician and mentors, the Physician Assistant Fellow manages therapeutic regimens for acute and chronic problems associated with such disease, treatment and/or conditions. The Physician Assistant Fellow provides anticipatory guidance, patient and family education, and psychological and emotional support. The Physician Assistant Fellow has prescrip

Pharmacy Technician Duties Practices as a pharmacy technician in accordance with all federal, state, DFCI and Joint Commission policies, regulations and standards. Fills medication orders according to policy, including proficiency with the most complex prescriptions and compounds. Ensures timely delivery and/or completion of medication orders and/or supplies. Utilizes mul

Collaborate with research pharmacy management team to oversee the daily operations to ensure that research pharmacy activities and services are carried out to meet all regulatory and institutional standard. Participate in the development and implementation of efficient workflows within the research pharmacy. Participate in and lead quality improvement initiatives and proj

Practices in accordance with all federal (e.g., Drug Supply Chain Security Act), state, and DFCI and Joint Commission policies, regulations, and standards. Responsible for all pharmacy inventory related activities such as commercial drug storage within the pharmacy, clinic and satellite locations, auditing inventory transactions, reviewing short dated drugs to ensure prop

Practices as a pharmacist in accordance with all federal, state, DFCI, DF/HCC, and Joint Commission policies, regulations, and standards. Appropriately prepares and dispenses pharmaceuticals, including non sterile and sterile products, investigational medications, hazardous drugs, biologics, and controlled substance medications clarifying order appropriateness with other